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This book details contemporary approaches to treating advanced cancers, focusing on liver and pancreatic malignancies. It examines targeted therapies, including RNA interference for pancreatic cancer and antibody-linked curcumin for hCG-expressing tumors. The text also covers next-generation immunotoxins, herbal remedies for HPV-related cervical cancer, and therapeutic vaccines targeting oncogenic HPV proteins. Further discussions include optimizing antigens and cellular components for anti-cancer vaccines and immunotherapy, alongside clinical findings on Mycobacterium indicus pranii's benefits.