By Yaffe
Yaffe, 2010
Written by experts at the forefront of current research and clinical practice, this book provides evidence-based guidelines for safe, effective, and rational drug therapy in newborns, children, and adolescents. It covers specific recommendations for all major drug classes and diseases, a detailed section on drugs and the newborn, and chapters on specific treatment settings such as the pediatric intensive care unit and emergency room. Advanced topics include adverse effects, interactions, pharmacokinetics, pharmacodynamics, pharmacogenetics, pharmacogenomics, pharmacoproteomics, drug development, and clinical trials in infants and children. Appendices feature a neonatal and a pediatric formulary. The Fourth Edition includes updated information on drug interactions and regulatory issues, plus new chapters on nutrient supplements and biotransformation of medications by the human placenta.