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This volume delves into the current state and future potential of cardiac regeneration and repair. It examines various techniques developed for heart failure treatment, including direct cell injection, reprogramming scar tissue into functional heart muscle, and the use of tissue-engineered heart muscle supports. The book outlines the rationale behind these cell-based regeneration approaches and discusses crucial considerations for their clinical application. Expert contributors explore methods for salvaging heart muscle, detailing when, why, and how it can be achieved.